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>The impact of healthy aging on molecular programming of immune cells is poorly understood. Here we report comprehensive characterization of healthy aging in human classical monocytes, with a focus on epigenomic, transcriptomic and proteomic alterations, as well as the corresponding proteomic and metabolomic data for plasma, using healthy cohorts of 20 young and 20 older males (~27 and ~64 years old on average).

>Ahead of the launch of Nature Aging in January 2021, the editors of the journal have curated an online Collection of recent papers on aging, longevity and age-related diseases published by Nature Research.
>This Collection reflects the increasingly multidisciplinary nature of the aging field and its numerous ramifications in other fields. Featuring such diversity is one of the aims of Nature Aging.
>The journal will address aging as a broad theme by publishing primary research articles, reviews and opinion pieces on the biology of aging, but also translational and clinical studies on age-related diseases, and observations and analyses that are relevant for public health and societal issues.
>The recently published articles gathered in this Collection are a testimony to how much the field has grown and diversified.